A new federal rule, OMB 0034-2026, hands the White House direct political control over every federal research grant. Buried in dull bureaucratic language, it lets the Office of Management and Budget—now run by Project 2025 architect Russell Vought—override the individual agencies that have always tailored their own grant processes. Its core move, Section 200.205, installs presidential appointees inside every agency with sole authority to approve or deny grants. Peer review by working scientists still happens, but its verdicts become merely advisory—and appointees are actually pressured to reject the proposals experts rate highest. Grants must align with administration priorities, can be killed at any time on a whim, and are barred from researchers tied to advocacy groups, foreign collaborators, or public communication. The OMB actuaries no longer just audit; they command. It is a unitary seizure of power over American science, the very basis of our prosperity and standard of living, and the time to fight it is now through public comments